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Biochemical Basis for the Enhanced Toxicity of Deoxyribonucleosides toward Malignant Human T Cell Lines

✍ Scribed by Dennis A. Carson, Jonathan Kaye, Steven Matsumoto, J. E. Seegmiller and Linda Thompson


Book ID
123655732
Publisher
National Academy of Sciences
Year
1979
Tongue
English
Weight
847 KB
Volume
76
Category
Article
ISSN
0027-8424

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lmmunotoxins (ITS) were prepared by covalently coupling r i c h to monoclonal antibodies (MAbs) directed against: (a) 2 different epitopes of the T-cell receptor (TcR) expressed by the Jurkat leukemia T-cell line UTi, and JTi, MAb), (b) 2 epitopes of the CD3 complex (SpV-T3b and I ID8 MAb), (c) the