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Biochemical bases of the interaction of human basic fibroblast growth factor with glycosaminoglycans : New insights from trypsin digestion studies

โœ Scribed by Daniela COLTRINI; Marco RUSNATI; Giorgio ZOPPETTI; Pasqua ORESTE; Antonella ISACCHI; Paolo CACCIA; Laura BERGONZONI; Marco PRESTA


Book ID
115130027
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
848 KB
Volume
214
Category
Article
ISSN
1432-1327

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Interaction of heparin with human basic
โœ Andreas Sommer; Daniel B. Rifkin ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 595 KB

Fibroblast growth factors (FGF) are a family of heparin-binding angiogenic polypeptide mitogens. In the presence of heparin, recombinant human basic fibroblast growth factor (bFGF) is fully protected from tryptic digestion and partially protected from chymotryptic digestion. Complete protection of b