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Biochemical and genetic characterization of the lowell variant. A new phenotype of 6-phosphogluconate dehydrogenase

✍ Scribed by M. S. Nelson

Publisher
Springer
Year
1982
Tongue
English
Weight
544 KB
Volume
62
Category
Article
ISSN
0340-6717

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The molecular nature of lethal and semilethal mutations in the Pgd locus of D. melanogaster coding for 6-phosphogluconate dehydrogenase (6PGD) was studied. All the 11 mutations affect the structural gene of the Pgd locus: 3 semilethal mutations resulted in altered 6PGD molecules with decreased catal