Estrogen produced in cultured hippocampa
Estrogen produced in cultured hippocampal neurons is a functional regulator of a GABAergic machinery
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Takamitsu Ikeda; Norio Matsuki; Maki K. Yamada
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Article
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2006
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John Wiley and Sons
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English
⚖ 210 KB
## Abstract Accumulating evidence suggests that estrogen is produced locally by the neurons in the brain. We observed that a 48‐hr treatment with the estrogen receptor antagonists ICI 182780 and tamoxifen decreased the level of glutamate decarboxylase (GAD)‐65, a rate‐limiting γ‐aminobutyric acid (