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Biochemical and cellular effects of a novel cyclin-dependent kinase inhibitor

✍ Scribed by R. Jorda; V. Krystof; L. Havlícek; M. Strnad

Book ID
119598729
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
89 KB
Volume
6
Category
Article
ISSN
1359-6349

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Cellular effects of purvalanol A: A specific inhibitor of cyclin-dependent kinase activities
✍ Nathalie Villerbu; Anne-Marie Gaben; Gérard Redeuilh; Jan Mester 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 630 KB

## Abstract We have studied the effects of purvalanol A on the cell cycle progression, proliferation and viability. In synchronized cells, purvalanol A induced a reversible arrest the progression in G1 and G2 phase of the cell cycle, but did not prevent the completion of DNA synthesis in S‐phase ce