✦ LIBER ✦

Biochemical and biological properties of methotrexate analogs containing d-glutamic acid or d-erythro,threo-4-fluoroglutamic acid

✍ Scribed by John J. McGuire; Wanda E. Bolanowska; James K. Coward; Roger F. Sherwood; Cynthia A. Russell; Donna M. Felschow

Book ID: 115782152
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 525 KB
Volume: 42
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(91)90247-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

New stereospecific syntheses and x-ray d

New stereospecific syntheses and x-ray diffraction structures of (−)-D-erythro- and (+)-L-threo-4-fluoroglutamic acid

✍ Milos Hudlicky; Joseph S. Merola 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 282 KB

Abrrracr . Stereospecific syntheses of (+)-L-rlrreo and (-)-D-eryrhro-4-fluoroglutamic acid am based on the hydrolysis of methyl l-acetyl-4-fluoro-L-pyrroklin-5-one-2-carboxylate, prepared from rrans-and cis-4hydmxyproliues, respectively. After the discovery of the antimetabolic properties of fluoro

Synthesis and Biological Activity of Fol

Synthesis and Biological Activity of Folic Acid and Methotrexate Analogues Containing l - threo -(2 S, 4 S )-4-Fluoroglutamic Acid and dl -3,3-Difluoroglutamic Acid

✍ Hart, Barry P.; Haile, William H.; Licato, Nicholas J.; Bolanowska, Wanda E.; Mc 📂 Article 📅 1996 🏛 American Chemical Society 🌐 English ⚖ 425 KB

ChemInform Abstract: Synthesis and Biolo

ChemInform Abstract: Synthesis and Biological Activity of Folic Acid and Methotrexate Analogues Containing L-threo-(2S,4S)-4-Fluoroglutamic Acid and DL-3,3- Difluoroglutamic Acid.

✍ B. P. HART; W. H. HAILE; N. J. LICATO; W. E. BOLANOWSKA; J. J. MCGUIRE; J. K. CO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB

Synthesis and biological activities of o

Synthesis and biological activities of oxytocin and lysine vasopressin analogs containing glutamic acid γ-hydrazide in position 4

✍ GAZIS, DIANA ;GLASS, JOHN ;SCHWARTZ, I. L. ;STAVROPOULOS, G. ;THEODOROPOULOS, D. 📂 Article 📅 2009 🏛 Wiley (Blackwell Publishing) 🌐 English ⚖ 416 KB

Synthesis and biological activity of an

Synthesis and biological activity of an acyclic analog of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl]amino]benzoyl]-L-glutamic acid [Erratum to document cited in CA112(7):56616d]

✍ Kelley, James L.; McLean, Ed W.; Cohn, Naomi K.; Edelstein, Mark P.; Duch, David 📂 Article 📅 1990 🏛 American Chemical Society 🌐 English ⚖ 118 KB

Opioid peptides: synthesis and biologica

Opioid peptides: synthesis and biological properties of [(Nγ-glucosyl,Nγ-methoxy)-α,γ-diamino-(S)-butanoyl]4-deltorphin-1-neoglycopeptide and related analoguesWith the exception of d-Ala the amino acid residues are of l-configuration. Standard abbreviations for amino acid derivatives and peptides are according to the suggestions of the IUPAC-IUB Commission on Biochemical Nomenclature, Eur. J. Biochem., 1984, 138, 9–37 and of J. Pept. Sci. 2003, 9, 1–8.

✍ Filira, Fernando; Biondi, Barbara; Biondi, Laura; Giannini, Elisa; Gobbo, Marina 📂 Article 📅 2003 🏛 Royal Society of Chemistry 🌐 English ⚖ 127 KB