Biochemical activity of intestinal microflora in adult coeliac disease
β Scribed by Tamm, A. O.
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 207 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0027-769X
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β¦ Synopsis
In order to answer up to now open questions regarding the role of the microflora in the pathophysiology of adult coeliac disease the excretion of bacterial metabolites in urine has been followed. Unusual high outputs of p-cresol and/or phenol were found in almost all patients. whereas an increased excretion of indican could be observed in a few persons. only. The response to short-term antibacterial therapy was variable.
π SIMILAR VOLUMES
One hundred twenty-five small intestinal biopsies of coeliac children and controls were investigated prospectively for gliadin binding by specific immunofluorescent staining of lamina propria cells, using a TRITC rabbit IgG antigliadinconjugate. In parallel, sera were investigated for serum gliadin