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Bioavailable estradiol and age at onset of Alzheimer's disease in postmenopausal women with Down syndrome

✍ Scribed by Nicole Schupf; Susan Winsten; Bindu Patel; Deborah Pang; Michel Ferin; Warren B. Zigman; Wayne Silverman; Richard Mayeux


Book ID
116768936
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
119 KB
Volume
406
Category
Article
ISSN
0304-3940

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Women with Down's syndrome experience early onset of both menopause and Alzheimer's disease. This timing provides an opportunity to examine the influence of endogenous estrogen deficiency, indicated by age at menopause, on risk of Alzheimer's disease. A community-based sample of 163 postmenopausal w