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Bioavailability of Phenytoin Acid and Phenytoin Sodium with Enteral Feedings

โœ Scribed by Karen K. Doak; Curtis E. Haas; Karin J. Dunnigan; Robert A. Reiss; Janet R. Reiser; Jeff Huntress; Jeanette L. Altavela

Book ID
112113752
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
841 KB
Volume
18
Category
Article
ISSN
0277-0008

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Dissolution behavior and bioavailability
Dissolution behavior and bioavailability of phenytoin from a ground mixture with microcrystalline cellulose
โœ Keiji Yamamoto; Masahiro Nakano; Takaichi Arita; Yoshikazu Takayama; Yoshinobu N ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 557 KB

The ground mixture of phenytoin and microcrystalline cellulose was prepared by grinding in a vibrational ball mill. The X-ray diffraction patterns indicated the amorphous nature of the ground mixture. Comparative studies were made concerning the in vitro dissolution and in vivo absorption of fine ph