Bioavailability of metformin in tablet form using a new high pressure liquid chromatography assay method

✍ Scribed by Gilles Caillé; Yves Lacasse; Manon Raymond; Hélène Landriault; Maria Perrotta; Gianfranca Picirilli; Jean Thiffault; Jean Spénard

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 308 KB
• Volume: 14
• Category: Article
• ISSN: 0142-2782
• DOI: 10.1002/bdd.2510140308

✦ Synopsis

Twenty-four young healthy volunteers received a single dose of metformin 500 mg (Glucophage@ , Nordic Laboratories, Canada) in tablet form. Plasma concentrations were determined by HPLC in samples collected prior to and 0.33, 0.