𝔖 Bobbio Scriptorium
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Bioavailability of antisense oligonucleotides in neuroblastoma cells: comparison of efficacy among different types of molecules

✍ Scribed by Maria Valeria Corrias; Francesco Guarnaccia; Mirco Ponzoni


Book ID
110228640
Publisher
Springer US
Year
1997
Tongue
English
Weight
113 KB
Volume
31
Category
Article
ISSN
0167-594X

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## Abstract Activation of the nuclear enzyme poly(ADP‐ribose)‐1 leads to the death of neurons and other types of cells by a mechanism involving NAD^+^ depletion and mitochondrial permeability transition. It has been proposed that the mitochondrial permeability transition (MPT) is required for NAD^+