Differences among cell types in NAD+ com
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Conrad C. Alano; Alexandra Tran; Rong Tao; Weihai Ying; Joel S. Karliner; Raymon
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Article
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2007
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John Wiley and Sons
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English
β 299 KB
## Abstract Activation of the nuclear enzyme poly(ADPβribose)β1 leads to the death of neurons and other types of cells by a mechanism involving NAD^+^ depletion and mitochondrial permeability transition. It has been proposed that the mitochondrial permeability transition (MPT) is required for NAD^+