Bioavailability assessment of ketoprofen incorporated in gelled self-emulsifying formulation: A technical note

Comparative bioavailability study in dog

Comparative bioavailability study in dogs of a self-emulsifying formulation of progesterone presented in a pellet and liquid form compared with an aqueous suspension of progesterone

✍ Catherine Tuleu; Michael Newton; Jayna Rose; Danielle Euler; Robert Saklatvala; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 105 KB

A pellet formulation of progesterone in a self-emulsifying system (SES) was prepared by the process of extrusion/spheronization to provide a good in vitro drug release (100% within 30 min, T 50% at 13 min). A three-way randomized crossover study was performed in six fasted male beagle dogs with thes