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Bioactive Xenicane Diterpenoids from the Taiwanese Soft Coral Asterospicularia laurae

✍ Scribed by Yun-Sheng Lin; Ahmed Eid Fazary; Chung-Hsiung Chen; Yao-Haur Kuo; Ya-Ching Shen


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
235 KB
Volume
8
Category
Article
ISSN
1612-1872

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✦ Synopsis


Abstract

Chemical investigation of the Taiwanese soft coral Asterospicularia laurae has led to the isolation of three new xenicane diterpenoids, named asterolaurins K–M (13, resp.). Their chemical structures were determined through extensive spectroscopic analyses (^1^H‐ and ^13^C‐NMR, ^1^H,^1^H‐COSY, HMBC, and NOESY). Compound 2 exhibited cytotoxic activity against HEp‐2, Daoy, MCF‐7, and WiDr tumor cells.


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