Four new xenicane diterpenoids, asterolaurins G -J (1 -4, resp.) have been isolated from the Taiwanese soft coral Asterospicularia laurae. Their structures were determined by extensive spectroscopic analyses (UV, CD, IR, 1 H-and 13 C-NMR, 1 H, 1 H-COSY, HMBC, and NOESY). The cytotoxic activities of
Bioactive Xenicane Diterpenoids from the Taiwanese Soft Coral Asterospicularia laurae
✍ Scribed by Yun-Sheng Lin; Ahmed Eid Fazary; Chung-Hsiung Chen; Yao-Haur Kuo; Ya-Ching Shen
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 235 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1612-1872
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✦ Synopsis
Abstract
Chemical investigation of the Taiwanese soft coral Asterospicularia laurae has led to the isolation of three new xenicane diterpenoids, named asterolaurins K–M (1–3, resp.). Their chemical structures were determined through extensive spectroscopic analyses (^1^H‐ and ^13^C‐NMR, ^1^H,^1^H‐COSY, HMBC, and NOESY). Compound 2 exhibited cytotoxic activity against HEp‐2, Daoy, MCF‐7, and WiDr tumor cells.
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