✦ LIBER ✦

Bioactive conformation of linear peptides in solution: An elusive goal?

✍ Scribed by Piero A. Temussi; Delia Picone; Maria A. Castiglione-Morelli; Andrea Motta; Teodorico Tancredi

Publisher: Wiley (John Wiley & Sons)
Year: 1989
Tongue: English
Weight: 1022 KB
Volume: 28
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360280112

No coin nor oath required. For personal study only.

✦ Synopsis

Bioactive peptides of natural origin have, in general, short linear sequences, and are characterized by a large conformational flexibility. I t is very difficult to study their conformation in solution since they exist, almost invariably, as a complex mixture of numerous conformers, most of which are extended. The so-called bioactive conformation may be one of them, although

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