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Binding Sites for Bilobalide, Diltiazem, Ginkgolide, and Picrotoxinin at the 5-HT3 Receptor

✍ Scribed by Thompson, A. J. (author);Duke, R. K. (author);Lummis, Sarah C.R. (author)

Book ID
118026212
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2011
Tongue
English
Weight
789 KB
Volume
80
Category
Article
ISSN
0026-895X

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## Abstract In an attempt to develop a specific probe of serotonin 5‐HT~3~ receptors, various methods have been investigated to synthesize a radioiodinated derivative of the potent 5‐HT~3~ antagonist zacopride. The direct iodination of 5‐dechloro‐zacopride 2 was performed using NaI in the presence