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Binding site of C-reactive protein on M-ficolin

✍ Scribed by Michikazu Tanio; Kaori Wakamatsu; Toshiyuki Kohno

Book ID
116757577
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
554 KB
Volume
47
Category
Article
ISSN
0161-5890

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C-reactive protein (CRP), the prototypical inflammatory acute phase reactant in humans, interacts with monocytes and neutrophils via a specific receptor. To map the site on CRP recognized by the CRP receptor (CRP-R), synthetic peptides corresponding to the surface region on each of the five identica