Binding site analysis using linear programming
β Scribed by Brassard, Pierre; Kramer, James R.; Collins, Pamela V.
- Book ID
- 127170156
- Publisher
- American Chemical Society
- Year
- 1990
- Tongue
- English
- Weight
- 887 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0013-936X
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Electrostatic binding sites of extracellular polymeric substances (EPS) were characterized from titration data using linear programming analysis. Test results for three synthetic solutions of given solutes comprising amino, carboxyl, and phenolic groups indicated that this method was able to identif
## Abstract This paper describes a new formulation, based on linear finite elements and nonβlinear programming, for computing rigorous lower bounds in 1, 2 and 3 dimensions. The resulting optimization problem is typically very large and highly sparse and is solved using a fast quasiβNewton method w