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Binding ofβ-adrenoceptor blocking drugs to human serum albumin, to α1-acid glycoprotein and to human serum

✍ Scribed by F. M. Belpaire; M. G. Bogaert; M. Rosseneu


Publisher
Springer
Year
1982
Tongue
English
Weight
416 KB
Volume
22
Category
Article
ISSN
0031-6970

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The feature of brucine binding to human serum albumin (HSA) was investigated via fluorescence and UV/vis absorption spectroscopy. The results revealed that brucine caused the fluorescence quenching of HSA by the formation of brucine-HSA complex. The hydrophobic interaction plays a major role in stab