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Binding of transferrin-iron by adriamycin at acidic pH

✍ Scribed by Erland J.F. Demant; Niels Nørskov-Lauritsen

Book ID
115917899
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
348 KB
Volume
196
Category
Article
ISSN
0014-5793

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✍ Robert J. Donohoe 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB 👁 1 views

Difference infrared spectra are reported for human serum transferrin in D2O as a function of iron binding or increased acidity. Spectral features detected as iron is bound at high pH include difference bands that are indicative of reduced solvent exposure and binding site ligation. More extensive sp