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Binding of the carboxyl-terminal fragments of human parathyroid hormone to rat osteoblastic cells ROS 17/2.8

✍ Scribed by Hisashi Takasu; Hisamitsu Baba; Yasushi Uchiyama; Noriyuki Inomata; Naoki Kubota; Kiichiro Nakajima; Terutoshi Kimura; Shumpei Sakakibara; Kenji Kumaki; Kazuo Chihara; Isamu Nagai; Etsuro Ogata


Publisher
Springer
Year
1994
Tongue
English
Weight
316 KB
Volume
12
Category
Article
ISSN
0914-8779

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ROS17/2.8 cells, a cell line derived from a rat osteosarcoma, have abundant receptors for parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP). A particulate membrane fraction was prepared from these cells and it was solubilized using relatively mild conditions with digitonin (0