Binding of the Alzheimer amyloid β-peptide to neuronal cell membranes by fluorescence correlation spectroscopy
✍ Scribed by Shakil Hossain; Mirtha Grande; Galib Ahmadkhanov; Aladdin Pramanik
- Book ID
- 113956513
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 228 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0014-4800
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## Abstract Neuronal pathology of the brain with Alzheimer's disease (AD) is characterized by numerous depositions of amyloid‐β peptides (Aβ). Aβ binding to the 75‐kDa neurotrophin receptor (p75NTR) causes neuronal cell death. Here we report that Aβ causes cell death in neuronal hybrid cells transf