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Binding of the 5-HT3 ligand, [3H]GR65630, to rat area postrema, vagus nerve and the brains of several species

✍ Scribed by Gavin J. Kilpatrick; Brian J. Jones; Michael B. Tyers

Book ID
115882721
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
552 KB
Volume
159
Category
Article
ISSN
0014-2999

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Membrane-Bound and solubilized brain 5HT3 receptors: Improved radioligand binding assays using bovine area postrema or rat cortex and the radioligands 3H-Gr65630C, 3H-BRl43694, and 3H-LY278584
✍ Keith Miller; Ellen Weisberg; Paul W. Fletcher; DR. Milt Teitler πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 866 KB

Bovine area postrema tissue was used as a convenient source of tissue for studies of brain 5HT3 receptors. 5HT3 receptor density was determined to be 97 5 5 fmoVmg and 124 k 10 fmoVmg of protein using the commercially available 5HT3 radioligands, 3H-GR65630 and 3H-BRL43694, respectively. The equilib