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Binding of tetrodotoxin and saxitoxin to Na+ channels at different holding potentials: fluctuation measurements in frog myelinated nerve

✍ Scribed by U. Lönnendonker


Book ID
115729054
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
473 KB
Volume
985
Category
Article
ISSN
0005-2736

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Interaction of monovalent cations with t
✍ U. Lönnendonker; B. Neumcke; R. Stämpfli 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 978 KB

Na currents and Na-current fluctuations were measured in myelinated frog nerve fibres to study interactions between monovalent externally applied cations and the binding of the Na-channel blockers tetrodotoxin (TTX) or saxitoxin (STX). Adding ll0mM NaC1 to Ringer's solution increased the maximum pea