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Binding of tetanus toxin by muscle sarcosomes in the presence of antitoxins

โœ Scribed by N. G. Bondarchuk

Publisher
Springer US
Year
1973
Tongue
English
Weight
184 KB
Volume
76
Category
Article
ISSN
0007-4888

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Immunization does not interfere with uptake and transport by motor neurons of the binding fragment of tetanus toxin
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## Abstract The nontoxic binding domain of tetanus toxin (fragment C or TTC) readily undergoes retrograde axonal transport from an intramuscular injection site. This property has led to investigation of TTC as a possible vector for delivering therapeutic proteins to motor neurons. However, the vast