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Binding of prion proteins to lipid membranes

✍ Scribed by Peter Critchley; Jurate Kazlauskaite; Robert Eason; Teresa J.T Pinheiro

Book ID: 116287690
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 199 KB
Volume: 313
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2003.12.004

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## Abstract We describe a new approach to calculate the binding of flexible peptides and unfolded proteins to multicomponent lipid membranes. The method is based on the transfer matrix formalism of statistical mechanics recently described as a systematic tool to study DNA–protein–drug binding in ge