Binding of platinum(II) intercalation reagents to deoxyribonucleic acid. Dependence on base-pair composition, nature of the intercalator, and ionic strength

Binding of the cationic 5-coordinate Zn(

Binding of the cationic 5-coordinate Zn(II)-5,10,15,20-tetrakis(4-N-methylpyridyl)porphyrin to DNA and model polynucleotides: Ionic-strength dependent intercalation in [poly(dG-dC)]2

✍ Vladimir S. Chirvony; Victor A. Galievsky; Sergei N. Terekhov; Boris M. Dzhagaro 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB 👁 1 views

The localization of the water-soluble cationic porphyrin ZnTMpyP(4) [Zn(II) derivative of 5,10,15,20-tetrakis(4-N-methylpyridyl)porphyrin] in its complex with [poly(dG-dC)] 2 is studied as a function of the solution ionic strength ( ϭ 0.20 -0.03). It is shown that the position of the Soret band maxi