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Binding of p-Cresylsulfate and p-Cresol to Human Serum Albumin Studied by Microcalorimetry

✍ Scribed by Bergé-Lefranc, David; Chaspoul, Florence; Calaf, Raymond; Charpiot, Philippe; Brunet, Philippe; Gallice, Philippe


Book ID
126821782
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
155 KB
Volume
114
Category
Article
ISSN
0022-3654

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Binding sites on human serum albumin (HSA) for anionic drugs and fatty acids have been thermodynamically characterized by microcalorimetry. The binding and the thermodynamic parameters were directly computed from the calorimetric titration data at 37 "C in a phosphate buffer (pH 7.4) using one-and t