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Binding of nonsteroidal anti-inflammatory agents and their effect on binding of racemic warfarin and its enantiomers to human serum albumin

✍ Scribed by Frank J. Diana; Karen Veronich; Amrit L. Kapoor

Book ID
118284736
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
592 KB
Volume
78
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES

Structural requirements for binding of n
Structural requirements for binding of nonsteroidal anti-inflammatory drugs to human serum albumin
✍ Kim L. Li; Ajit K. Thakur; Amrit L. Kapoor πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 541 KB

The binding of representative chemical classes of nonsteroidal anti-inflammatory drugs (NSAIDs) to human serum albumin (HSA) was investigated by equilibrium dialysis. Warfarin enantiomers were used as specific markers in displacement studies. Data were analyzed by a computerized nonlinear least squa