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Binding of kunitz and eglin c inhibitors to serine proteinases: thermodynamic, kinetic and molecular aspects

โœ Scribed by Paolo Ascenzi; Gino Amiconi; Martino Bolognesi; Enea Menegatti; Mario Guarneri


Book ID
103692805
Publisher
Elsevier Science
Year
1988
Weight
633 KB
Volume
47
Category
Article
ISSN
0304-5102

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Binding of the recombinant proteinase in
โœ Paolo Ascenzi; Patrizia Aducci; Gino Amiconi; Alessandro Ballio; Alberto Guaragn ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 679 KB

## Abstract The binding of the recombinant proteinase inhibitor eglin __c__ from the leech __Hirudo medicinalis__ to serine (pro)enzymes belonging to the chymotrypsin and subtilisin families has been investigated from the thermodynamic viewpoint, between pH 4.5 and 9.5 and from 10ยฐC to 40ยฐC. The af