rapidly. There is a need to characterize the reactions oc-Analyte-receptor binding reactions occurring on biosensor surcurring at the biosensor surface, by paying attention to both faces are categorized using a fractal analysis. Both a single-and the reaction and the sensing element (surface). Seri-Levy a dual-fractal analysis are utilized to describe the analyte-receptor and Avnir (1991) emphasize that antigen-antibody reacbinding kinetics. The three categories presented to describe the tions are influenced not only by the chemistry involved but binding kinetics include (a) case I-only a single-fractal analysis also by the geometry of the environment in which the bindis utilized, (b) case II-a single-and a dual-fractal analysis are ing takes place.
utilized (implying a change in the binding mechanism), and (c)
External diffusional limitations play a role in immunoascase III-only a dual-fractal analysis is utilized. This is an initial says (Bluestein et al., 1991; Eddowes, 1987 Eddowes, /1988; Place et attempt to categorize surface binding kinetics. The categorization provides one possible means of classifying analyte-receptor reac- al., 1991; Giaver, 1976). The influence of diffusion in such tions occurring on biosensor surfaces. The analysis should help to systems has been analyzed to some extent (Place et al., improve biosensor performance parameters. The analysis is,