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Binding constants of soluble NGF-receptors in rat oligodendrocytes and astrocytes in culture

✍ Scribed by Dario Marchetti; Robert W. Stach; Russell Saneto; Jean de Vellis; J. Regino Perez-Polo

Book ID
117057499
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
274 KB
Volume
147
Category
Article
ISSN
0006-291X

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Insulin-like growth factors, IGF-I and IGF-II, are potent regulators of oligodendrocyte development. Most of the IGF present in vivo is bound to members of a family of six high-affinity IGF-binding proteins (IGFBPs), which can either potentiate or inhibit IGF action, depending on other conditions. A