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Binding and Phosphorylation of Par-4 by Akt Is Essential for Cancer Cell Survival

✍ Scribed by Anindya Goswami; Ravshan Burikhanov; Aurelie de Thonel; Naoya Fujita; Mamta Goswami; Yanming Zhao; John E. Eriksson; Takashi Tsuruo; Vivek M. Rangnekar

Book ID
116753978
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
643 KB
Volume
20
Category
Article
ISSN
1097-2765

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✍ Nanami Itoh; Shuho Semba; Masafumi Ito; Hiroaki Takeda; Sumio Kawata; Mitsunori πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 683 KB

## Abstract ## BACKGROUND Akt/protein kinase B (PKB), which is included in phosphatidyl inositol‐3‐OH kinase (PI3K) signaling, controls many intracellular processes, such as the suppression of apoptosis and the promotion of the cell cycle. Therefore, the authors investigated phosphorylated Akt (Se