Adhesion to collagens by most cell types is mediated by the integrins a1b1 and a2b1. Both integrin a subunits belong to a group which is characterized by the presence of an I domain in the N-terminal half of the molecule, and this domain has been implicated in the ligand recognition. Since purified
✦ LIBER ✦
Binding and Docking of Synthetic Heterotrimeric Collagen Type IV Peptides with α1β1 Integrin
✍ Scribed by Barbara Saccà; Eva-Kathrin Sinner; Jens Kaiser; Christoph Lübken; Johannes A. Eble; Luis Moroder
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 400 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1439-4227
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 1 integrins are widely expressed in human tissues but their presence and function on malignant mesothelioma cells have not been examined. In this study, we have investigated the expression and function of  1 integrins in 7 human malignant mesothelioma cell lines. Immunofluorescence staining and F