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Binding affinity of influenza virus N9 neuraminidase with Fab fragments of monoclonal antibodies NC10 and NC41

โœ Scribed by L. C. Gruen; T. L. McInerney; R. G. Webster; D. C. Jackson


Publisher
Springer
Year
1993
Tongue
English
Weight
425 KB
Volume
12
Category
Article
ISSN
1573-4943

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Analysis of the Binding of the Fab Fragm
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The binding of the Fab fragment of monoclonal antibody NC10 to influenza virus N9 neuraminidase, isolated from tern and whale, was measured using an optical biosensor. Both neuraminidases, homotetramers of 190 kDa, were immobilized to avoid multivalent binding, and the binding of the monovalent NC10