𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Binding Affinities of Host—Guest, Protein—Ligand, and Protein—Transition-State Complexes

✍ Scribed by K. N. Houk; Andrew G. Leach; Susanna P. Kim; Xiyun Zhang

Publisher
John Wiley and Sons
Year
2004
Weight
54 KB
Volume
35
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Binding constant determination of high-a
Binding constant determination of high-affinity protein–ligand complexes by electrospray ionization mass spectrometry and ligand competition
✍ Arno Wortmann; Matthias C. Jecklin; David Touboul; Martin Badertscher; Renato Ze 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 600 KB

## Abstract We describe an approach for the determination of binding constants for protein–ligand complexes with electrospray ionization mass spectrometry, based on the observation of unbound ligands competing for binding to a protein target. For the first time, dissociation constants lower than pi

Protein—DNA recognition complexes: Conse
Protein—DNA recognition complexes: Conservation of structure and binding energy in the transition state
✍ Linda Jen-Jacobson 📂 Article 📅 1997 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 665 KB

This paper considers how enzymes that catalyze reactions at specific DNA sites have been engineered to overcome the problem of competitive inhibition by excess nonspecific binding sites on DNA. The formation of a specific protein-DNA recognition complex is discussed from both structural and thermody