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Biliary transport of glutathione disulfide studied with isolated rat-liver canalicular-membrane vesicles

✍ Scribed by Theo AKERBOOM; Masayasu INOUE; Helmut SIES; Rolf KINNE; Irwin M. ARIAS


Book ID
115122470
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
467 KB
Volume
141
Category
Article
ISSN
1432-1327

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To study the effect of bile acids on P-glycoproteinmediated drug transport, we performed experiments using multidrug resistant cells and rat canalicular membrane vesicles. Cellular accumulation and efflux of rhodamine 123 were measured in drug-resistant cells by means of computerized quantitative im