Biliary excretion of copper, manganese, and horseradish peroxidase in eisai hyperbilirubinemic mutant rats (EHBRs) with defective biliary excretion of glutathione
โ Scribed by Naoki Sugawara; Yurong Lai; Motoyuki Yuasa; Sanjit Kumar Dhar; Koji Arizono
- Book ID
- 112892199
- Publisher
- Humana Press Inc
- Year
- 1996
- Tongue
- English
- Weight
- 514 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0163-4984
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๐ SIMILAR VOLUMES
Biliary excretion of methylmercury, a major route of elimination of this toxic compound, was less than 2% of control in Eisai hyperbilirubinemic (EHBR) rats, a mutant Sprague-Dawley strain with a defect in biliary excretion of a variety of organic anions, including glutathione S-conjugates and reduc
Dubin-Johnson patients, mutant Corriedale sheep and TRand EHBR mutant rats have recessively inherited defective bile canalicular secretion of many nonbile acid organic anions. The human and ovine mutants have black livers and lysosomal pigment accumulation. The livers in TR-and EHBR mutant rats are