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Biliary Drug Excretion and Stimulation of Bile Flow

✍ Scribed by Koss, Friedrich Wilhelm ;Pelzer, Helmut ;Kopitar, Zdravko


Book ID
114798773
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
375 KB
Volume
29
Category
Article
ISSN
0001-6683

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Interspecies scaling of biliary excreted
✍ Iftekhar Mahmood; Chandra Sahajwalla πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 80 KB

The objective of this study is to predict clearance of drugs in humans from animals which are excreted in the bile. Clearance (CL) of eight drugs known to be excreted in the bile were randomly selected from the literature. Scaling of CL was performed using at least three animal species. Using simple