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Biliary dilatation secondary to lithiasis in a child affected by Langerhans' cell histiocytosis

✍ Scribed by Settimo Caruso; Roberto Miraglia; Marco Spada; Angelo Luca; Bruno Gridelli


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
169 KB
Volume
37
Category
Article
ISSN
0091-2751

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✦ Synopsis


Abstract

Langerhans' cell histiocytosis (LCH) is a disease of unknown pathogenesis, caused by clonal proliferation of Langerhans' cells. Liver involvement results in a cholangiopathy, which has the radiologic appearance of sclerosing cholangitis. Only 1 case of obstructive jaundice due to common bile duct stone in a patient with LCH has been described. We present a case of a 31‐month‐old child with LCH and liver involvement on the waiting list for liver transplantation. During the follow‐up, there was a rapid onset of jaundice due to sludge and lithiasis. The patient was treated first with an endoscopic biliary plastic stent and then with percutaneous biliary drainage and bilioenteric anastomosis. © 2009 Wiley Periodicals, Inc. J Clin Ultrasound 2009