The hydrophilic-hydrophobic balance of bile salt monomers can be readily quantified by their elution sequence during reverse-phase high-performance liquid chromatography. Such studies have demonstrated that subtle variations in bile salt structure have profound effects on the hydrophilic-hydrophobic
โฆ LIBER โฆ
Bile salts
โ Scribed by Lucy, J. A.
- Book ID
- 109713495
- Publisher
- Nature Publishing Group
- Year
- 1979
- Tongue
- English
- Weight
- 131 KB
- Volume
- 278
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/278378b0
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Calcium binding to bile salt monomers and micelles is an important issue with respect to the possible (but rare) precipitation of calcium bile salts in the gallbladder. In the present work the binding of Ca 2+ to six bile salts was measured in solutions containing 2 to 100 mM bile salts by means of