## I We investigated whether bile concentration influenced cholesterol saturation index or nucleation time of cholesterol monohydrate crystals in a large number of gallbladder bile samples. Pigment stone patients never had cholesterol crystals in their fresh biles, and nucleation time was always l
✦ LIBER ✦
Bile concentration promotes nucleation of cholesterol monohydrate crystals by increasing the cholesterol concentration in the vesicles
✍ Scribed by K. J. VAN ERPECUM; M. F. J. STOLK; A. M. W. C. VAN DEN BROEK; W. RENOOIJβ; B. J. M. VAN DE HEIJNING; G. P. VAN BERGE HENEGOUWEN
- Book ID
- 114727218
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 639 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0014-2972
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3-hydroxy,3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors reduce biliary cholesterol saturation index (CSI) in duodenal bile in hypercholesterolemic patients and might be useful for gallstone dissolution. However, preliminary data suggest that these drugs are not effective in this respect