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Bile acids in deermice lacking liver alcohol dehydrogenase

✍ Scribed by Jan Sjövall; Stig H.G. Andersson; Charles S. Lieber


Book ID
115739288
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
601 KB
Volume
836
Category
Article
ISSN
0005-2760

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Hepatotoxicity due to allyl alcohol in d
✍ Steven A. Belinsky; Blair U. Bradford; Donald T. Forman; Edward B. Glassman; Mic 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 462 KB

The role of alcohol dehydrogenase in the hepatic necrosis due to allyl alcohol was studied in two strains of the deermouse, Peromyscus maniculatm. Mice of the alcohol dehydrogenase-negative (AdhN) strain which lack alcohol dehydrogenase activity were resistant to allyl alcohol toxicity. In contrast,