Bilateral preaxial polydactyly in a WAGR syndrome patient
β Scribed by Siranoush Manoukian; John A. Crolla; Palma M.A. Mammoliti; Maria Adele Testi; Rinaldo Zanini; Maria Luisa Carpanelli; Elena Piozzi; Gabriella Sozzi; Giovanna De Vecchi; Monica Terenziani; Filippo Spreafico; Paola Collini; Paolo Radice; Daniela Perotti
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 139 KB
- Volume
- 134A
- Category
- Article
- ISSN
- 1552-4825
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## Abstract The WAGR contiguous gene deletion syndrome is a combination of Wilms tumor, Aniridia, Genitoβurinary abnormalities, and growth and mental retardation which is invariably associated with an 11p13 deletion. We report two monozygotic twins and a third, unrelated patient with WAGR syndrome
## Abstract Wilms tumor, aniridia, genitourinary anomalies, and mental retardation (WAGR) syndrome is a contiguous gene deletion syndrome involving the Wilms tumor 1 gene (__WT1__), the paired box gene 6 (__PAX6__), and possibly other genes on chromosome 11p13. __WT1__ is required for normal format