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Big-endothelin 1 (big ET-1) and homocysteine in the serum of dogs with chronic kidney disease

✍ Scribed by Rossi, Gabriele; Giordano, Alessia; Breda, Sara; Lisi, Chiara; Roura, Xavier; Zatelli, Andrea; Paltrinieri, Saverio


Book ID
122613365
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
658 KB
Volume
198
Category
Article
ISSN
1090-0233

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## Abstract The complex pathogenesis of chronic renal disease (CRD) depends on endothelin (ET) axis (ETs and ET receptors) and nitric oxide (NO) because of their vasoactive effects and their role in general modulation of vascular homeostasis. Various renal cells synthesize ETs and NO that play a si