✦ LIBER ✦

Bifunctional inhibition of HIV-1 reverse transcriptase: A first step in designing a bifunctional triphosphate

✍ Scribed by Piao, Dongyuan; Basavapathruni, Aravind; Iyidogan, Pinar; Dai, Guangxiu; Hinz, Wolfgang; Ray, Adrian S.; Murakami, Eisuke; Feng, Joy Y.; You, Fei; Dutschman, Ginger E.; Austin, David J.; Parker, Kathlyn A.; Anderson, Karen S.

Book ID: 118178438
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 871 KB
Volume: 23
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2012.12.015

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of a difluoromethylenephosphon

Synthesis of a difluoromethylenephosphonate analogue of AZT 5'-triphosphate and its inhibition of HIV-1 reverse transcriptase

✍ D. Hebel; K.L. Kirk; J. Kinjo; T. Kovács; K. Lesiak; J. Balzarini; E. De Clercq; 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 339 KB

Combination of a mutagenic agent with a

Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection

✍ Natalia Tapia; Guerau Fernàndez; Mariona Parera; Gemma Gómez-Mariano; Bonaventur 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 408 KB

ChemInform Abstract: A Check on Rational

ChemInform Abstract: A Check on Rational Drug Design: Molecular Simulation of the Allosteric Inhibition of HIV-1 Reverse Transcriptase

✍ P. P. MAGER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 2 views

Restrained molecular dynamics simulation

Restrained molecular dynamics simulations of HIV-1 protease: The first step in validating a new target for drug design

✍ Alexander L. Perryman; Jung-Hsin Lin; J. Andrew McCammon 📂 Article 📅 2006 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 804 KB

## Abstract To test the anticorrelated relationship that was recently displayed in conventional molecular dynamics (MD) simulations, several different restrained MD simulations on a wild type and on the V82F/I84V drug‐resistant mutant of HIV‐1 protease were performed. This anticorrelated relationsh

The inhibition of human immunodeficiency

The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds

✍ Tara M. Brennan; Debra L. Taylor; C.Gordon Bridges; James P. Leyda; A.Stanley Ty 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 865 KB

Reversible inhibition of C1q release fro

Reversible inhibition of C1q release from guinea pig macrophages by 2,2′-dipyridyl: Evidence for a posttranslational hydroxylation step in the biosynthesis of C1q, a subcomponent of the first component of complement (C1)

✍ Wolfgang Müller; Hartmut Hanauske-Abel; Michael Loos 📂 Article 📅 1978 🏛 Elsevier Science 🌐 English ⚖ 443 KB