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Bifunctional chiral auxiliaries 4: Alkylation of enolates derived from 1,3-diacyl-trans-4,5-tetramethyleneimidazolidin-2-ones

✍ Scribed by Stephen G. Davies; Andrew A. Mortlock


Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
273 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis


Addition of alkyl halides to sodium and potassium enolates of 1,3-diacyl-trans-4,5-


πŸ“œ SIMILAR VOLUMES


The Chiral Glycine Enolate Derivative fr
✍ Dieter Seebach; David D. Miller; Stefan MΓΌller; Theodor Weber πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 German βš– 252 KB

## Abstract An overall enantioselective substitution of the R‐group of an α‐hydroxy‐ or α‐amino acid **1** [Rο£ΏCH(XH)COOH] by another R‐group is possible through heterocycles **2** obtained from **1** with pivaladehyde (**1 β†’ 7**). The __rac__‐ and the (__S__)‐(+)‐heterocycles **8** (title compounds