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Bidirectional differentiation involving a cell with rearrangement of the MLL gene

✍ Scribed by van der Schoot, C E; Kroes, W; Beverloo, H B; Slater, R; van den Berg, H; Caron, H N; Theunissen, P H M H; Theunissen, P M V M

Book ID
110053728
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
73 KB
Volume
12
Category
Article
ISSN
0887-6924

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## Abstract Here we report the case of a 7‐month‐old boy who presented with biphenotypic acute leukemia, but with leukemia cells of B‐cell phenotype present at the time of relapse. Two cell lines were derived from bone marrow specimens obtained at relapse, and immunophenotyping and analysis of anti