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Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells

โœ Scribed by Theodore O. Garnett; Maria Filippova; Penelope Jayne Duerksen-Hughes


Publisher
Springer
Year
2007
Tongue
English
Weight
759 KB
Volume
12
Category
Article
ISSN
1360-8185

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## Abstract Osteosarcoma is one of the most common primary malignant tumors of bone. Treatment of this tumor with systemic chemotherapy dramatically improves the prognosis, although the molecular mechanisms involved in the drug action are poorly understood. In chemosensitive leukaemic T cells and c