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Bicistronic vector for combined expression of theHSVtkkiller gene and cytokineGM-CSFgene in cancer cells

✍ Scribed by I. V. Alekseenko; E. P. Kopantzev; T. V. Vinogradova; E. D. Sverdlov

Book ID
111470187
Publisher
SP MAIK Nauka/Interperiodica
Year
2011
Tongue
English
Weight
637 KB
Volume
439
Category
Article
ISSN
1607-6729

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## Abstract ## Background Metastatic renal cell carcinoma (mRCC) is one of the most treatment‐resistant malignancies. Despite all new therapeutic advances, almost all patients develop resistance to treatment and cure is rarely seen. In the present study, we evaluated the antitumor effect of a bici