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Biased estimates of treatment effect in randomized trials

โœ Scribed by Gail, Mitchell; Wieand, Sam; Piantadosi, Steven


Book ID
122876340
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
82 KB
Volume
5
Category
Article
ISSN
0197-2456

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In clinical trials where patients are randomized between two treatment arms, not all patients comply with the treatment they were randomly assigned to. The reasons for (non)compliance may be associated with the outcome variable and thereby act as confounders. The standard way of analysing such trial